SCHEMBL27449710

SCHEMBL27449710

C[C@H](NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.67
▸ SLC7A5 Q01650 1/20 0.67
▸ HRH4 Q9H3N8 3/20 0.53
▸ HRH3 Q9Y5N1 3/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ GLA P06280 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ NFKB1 P19838 1/20 0.53
▸ THPO P40225 1/20 0.53
▸ LMNA P02545 1/20 0.51
▸ APEX1 P27695 1/20 0.51
▸ BLM P54132 1/20 0.51
▸ NLN Q9BYT8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30270561 1.00 CYP3A4 (0.67) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL12343824 0.89 CYP3A4 (0.58) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL15259275 0.89 CYP3A4 (0.58) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL8234259 0.88 CYP3A4 (0.57) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL31066572 0.87 CYP3A4 (0.63) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL18697423 0.87 CYP3A4 (0.56) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL17189358 0.87 CYP3A4 (0.56) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL12982022 0.87 CYP3A4 (0.56) CYP3A4SLC7A5HRH4HRH3ALDH1A1
SCHEMBL21828671 0.85 CYP3A4 (0.68) CYP3A4SLC7A5NLN
SCHEMBL29728766 0.85 CYP3A4 (0.60) CYP3A4SLC7A5HRH4HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111819191-B Chemoenzymatic synthesis of liraglutide, soxhlet Ma Lutai and GLP-1 费森尤斯卡比有限公司 2024-08-20 — — CN claimed
CN-113967258-B FAP-activated therapeutic agents and related uses 塔夫茨大学信托人 2024-07-02 — — CN claimed
CN-117202936-A Glucagon-like peptide compounds 诺华股份有限公司 2023-12-08 — — CN claimed
CN-116519811-A System for predicting blood glucose level of pregnant individual 杭州凯莱谱精准医疗检测技术有限公司 2023-08-01 — — CN claimed
CN-116519812-A Application of biomarker in preparation of gestational diabetes diagnostic reagent 杭州凯莱谱精准医疗检测技术有限公司 2023-08-01 — — CN claimed
EP-3758730-B1 PEPTIDES AND COMPOSITIONS FOR USE IN COSMETICS AND MEDICINE LIPOTRUE S L (ES) 2022-11-02 — — EP claimed
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ASTRAZENECA AB (SE) 2026-02-05 — — US disclosed
WO-2025259130-A1 USE OF AC-HIS-ALA-GLU-GLU-NH2 PEPTIDE TO REMEDY DEFICIT OF AN ENDOGENOUS COMPONENT OF ANIMAL BLOOD CONSUMER COOPERATIVE "VSE" 2025-12-18 — — WO disclosed
WO-2025259133-A1 AC-HIS-ALA-GLU-GLU-NH2 PEPTIDE AND DERIVATIVES THEREOF FOR REMEDYING DEFICIT OF AN ENDOGENOUS COMPONENT OF HUMAN BLOOD Федеральное государственное автономное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации 2025-12-18 — — WO disclosed
US-20250368605-A1 Novel Substituted 6,7-Dihydro-5H-Benzo[7]Annulene Compounds, Processes for their Preparation and Therapeutic Uses Thereof SANOFI (FR) 2025-12-04 — — US disclosed
US-20250277001-A1 PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS CENTESSA PHARMACEUTICALS UK LTD (GB) 2025-09-04 — — US disclosed
EP-4554968-A1 PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS Centessa Pharmaceuticals (UK) Limited (GB) 2025-05-21 — — EP disclosed
US-12297260-B2 DKK1 antibodies and methods of use AMGEN INC. (US) 2025-05-13 — — US disclosed
CN-109963848-B Substituted N- (3-fluoropropyl) -pyrrolidine compounds, preparation thereof and therapeutic use thereof 赛诺菲 2022-07-05 — — CN disclosed
CN-103477224-B Blood collection device containing lysophospholipase inhibitor BECTON, DICKINSON AND CO. (US) 2015-12-23 — — CN disclosed
CN-103477224-A Blood collection device containing lysophospholipase inhibitor BECTON DICKINSON CO 2013-12-25 — — CN disclosed
CN-1269528-C Application of dipeptide base peptidase IV effector for reducing blood sugar level of mammal BIOLOG MEDICINE AG (GB) 2006-08-16 — — CN disclosed
CN-1535681-A Application of dipeptide base peptidase IV effector for reducing blood sugar level of mammal ӡ��ҩƷ�ɷ����޹�˾ 2004-10-13 — — CN disclosed
CN-1132578-C Use of dipeptidyl peptidase IV effectors to lower blood glucose levels in mammals BIOLOG DRUG REAGENTS FOR PHARM (DE) 2003-12-31 — — CN disclosed
CN-1216468-A Use of dipeptidyl peptidase IV effectors to lower blood glucose levels in mammals BIOLOG DRUG REAGENTS FOR PHARM (DE) 1999-05-12 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368605-A1 Novel Substituted 6,7-Dihydro-5H-Benzo[7]Annulene Compounds, Processes for their Preparation and Therapeutic Uses Thereof CYP19A1, ESR1, ESR2 CYP3A4 168/4885SLC7A5 2562/4885HRH4 217/4885
US-20250277001-A1 PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS HCRTR2, HCRTR1, CRH CYP3A4 907/4885SLC7A5 1787/4885HRH4 218/4885
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ATP5ME, ATP5MF, ATP5MK CYP3A4 1949/4885SLC7A5 1133/4885HRH4 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback