Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450149 | 0.84 | ALDH1A1 (0.60) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL27419115 | 0.80 | KDM4E (0.41) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL7570690 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3587711 | 0.76 | TDP1 (0.64) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL24597630 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27418513 | 0.74 | PARP1 (0.51) | KDM4EALDH1A1AURKABACE1 | |
| SCHEMBL27450576 | 0.71 | KMT2A (0.42) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL7570787 | 0.71 | ABCG2 (0.49) | KMT2AKDM4EALDH1A1CYP1A2HTT | |
| SCHEMBL30009200 | 0.71 | BACE1 (0.46) | KDM4ECYP1A2CYP2C19HTTAKR1B1 | |
| SCHEMBL13739658 | 0.70 | PTGDR2 (0.54) | MEN1KMT2AKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |