Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.88 |
| ▸ | F3 | P13726 | 1/20 | 0.88 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.88 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.88 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.88 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.88 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.88 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.88 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.64 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.58 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL12003204 | 0.98 | F7 (0.85) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29141606 | 0.98 | F7 (0.85) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL675207 | 0.96 | F7 (0.96) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL27671762 | 0.94 | F7 (0.92) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29624874 | 0.94 | — | — | |
| Niacinamide SCHEMBL2926 | 0.94 | — | — | |
| Niacinamide SCHEMBL460466 | 0.94 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL19978192 | 0.94 | — | — | |
| Benzamide SCHEMBL594793 | 0.92 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL4601203 | 0.92 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117982466-B | Application containing sodium hyaluronate for surface anesthesia and preparation method thereof | 湖南新谐康医疗器械有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117982466-A | Application containing sodium hyaluronate for surface anesthesia and preparation method thereof | 湖南新谐康医疗器械有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-112390745-B | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112390745-B | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112390745-B | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112390745-A | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112390745-A | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112390745-A | Pyridine nicotinamide derivatives, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-110799217-A | Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates | 西雅图基因公司 | 2020-02-14 | — | — | CN | disclosed |
| CN-206298532-U | A kind of Boscalid intermediate prepares production pilot test system | 浙江荣凯科技发展股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-106748804-A | A kind of Boscalid intermediate 2（4 chlorphenyls）Aniline synthesis technique | 浙江荣凯科技发展股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| US-8180580-B2 | Method for identifying a compound that modulates SIR2 protein activity | THE WISTAR INSTITUTE (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090326007-A1 | Compounds and methods for modulating sir2 protein activity | THE WISTAR INSTITUTE | 2009-12-31 | — | — | US | disclosed |
| US-20080305496-A1 | Method for identifying a compound that modulates SIR2 protein activity | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-11 | — | — | US | disclosed |
| WO-2008095056-A2 | METHOD FOR IDENTIFYING A COMPOUND THAT MODULATES SIR2 PROTEIN ACTIVITY | THE WISTAR INSTITUTE (US) | 2008-08-07 | — | — | WO | disclosed |
| US-3957804-A | NICKEL AND IRON OXIDE HYDRATION CATALYSTS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326007-A1 | Compounds and methods for modulating sir2 protein activity | SIRT2, SIRT1, SIRT3 | F7 4793/4885F3 3398/4885SARM1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.