Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451704 | 0.85 | ALDH1A1 (0.51) | POLBMEN1MAPTKMT2AHPGD | |
| SCHEMBL10283866 | 0.85 | ALDH1A1 (0.51) | POLBMEN1MAPTKMT2AHPGD | |
| SCHEMBL19353252 | 0.85 | ALDH1A1 (0.51) | POLBMEN1MAPTKMT2AHPGD | |
| SCHEMBL10241495 | 0.85 | ALDH1A1 (0.51) | POLBMEN1MAPTKMT2AHPGD | |
| SCHEMBL462693 | 0.82 | HPGD (0.46) | POLBMEN1MAPTKMT2AHPGD | |
| SCHEMBL24348777 | 0.81 | ALDH1A1 (0.47) | POLBMEN1MAPTKMT2AHPGD | |
| SCHEMBL18904853 | 0.77 | JAK3 (0.43) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23547437 | 0.77 | JAK3 (0.43) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27451749 | 0.77 | JAK3 (0.43) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18909618 | 0.77 | JAK3 (0.43) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129395-A1 | BTK INHIBITORS | GWYNANT THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |