Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.69 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359341 | 0.95 | HDAC1 (0.77) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL30444296 | 0.85 | HDAC1 (0.80) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL24359677 | 0.85 | HDAC1 (0.78) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL17107235 | 0.84 | HDAC1 (0.77) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL5849033 | 0.84 | MAPK1 (0.79) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL29516444 | 0.83 | HDAC1 (0.72) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL27452889 | 0.83 | MAPT (0.61) | MAPTMAPK1RAB9AALDH1A1PKM | |
| SCHEMBL24359678 | 0.83 | HDAC1 (0.72) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL11479812 | 0.83 | HDAC1 (0.80) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL17107157 | 0.83 | HDAC1 (0.80) | HDAC1HDAC2HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |