Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 8/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453719 | 0.81 | CRBN (0.44) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL27453731 | 0.81 | CRBN (0.44) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL26930886 | 0.81 | CRBN (0.46) | CRBNDDB1IKZF3CSNK1A1ALDH1A1 | |
| SCHEMBL26930503 | 0.79 | CRBN (0.48) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL26930466 | 0.79 | CRBN (0.48) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL30659363 | 0.79 | CRBN (0.48) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL27454822 | 0.79 | CRBN (0.47) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL30796394 | 0.79 | TMEM97 (0.49) | CRBNDDB1IKZF3GAA | |
| SCHEMBL26930449 | 0.78 | CRBN (0.46) | CRBNDDB1IKZF3ALDH1A1KDM4E | |
| SCHEMBL26954254 | 0.78 | CRBN (0.52) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |