SCHEMBL27455142

SCHEMBL27455142

O=C(Nc1ccc(Cl)cc1)c1cc(Cl)cc(O)c1C(=O)Nc1scc(CCl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 3/20 0.47
F10 P00742 14/20 0.44
F2 P00734 8/20 0.43
KLKB1 P03952 1/20 0.41
P2RX4 Q99571 1/20 0.41
P2RX7 Q99572 1/20 0.41
TMPRSS4 Q9NRS4 1/20 0.41
ANO1 Q5XXA6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27470746 0.87 F10 (0.48) F10F2KLKB1
SCHEMBL27475920 0.83 F10 (0.63) F10F2
SCHEMBL6596512 0.79 F10 (0.59) F10F2
SCHEMBL27469751 0.76 F10 (0.49) F10F2KLKB1
SCHEMBL27550880 0.74 F10 (0.49) F10F2KLKB1
SCHEMBL6593184 0.73 F10 (0.77) F10F2
SCHEMBL27472143 0.72 F2 (0.66) F10F2
SCHEMBL27456727 0.72 F10 (0.49) F10F2KLKB1
SCHEMBL27454481 0.72 F2 (0.47) F10F2KLKB1
SCHEMBL27453701 0.71 F2 (0.47) F10F2KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1143855-C I (ortho)-anthranilamide derivatives as anti-coagulants ���ֹɷݹ�˾ 2004-03-31 CN disclosed