SCHEMBL27469751

SCHEMBL27469751

Nc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1C(=O)Nc1scc(CCl)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.49
F2 P00734 17/20 0.47
KLKB1 P03952 1/20 0.47
ELANE P08246 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27470746 0.90 F10 (0.48) F10F2KLKB1ELANE
SCHEMBL27550880 0.86 F10 (0.49) F10F2KLKB1ELANE
SCHEMBL27471246 0.85 F2 (0.65) F10F2
SCHEMBL27454481 0.84 F2 (0.47) F10F2KLKB1ELANE
SCHEMBL27471708 0.82 F10 (0.52) F10F2KLKB1ELANE
SCHEMBL27460548 0.82 F10 (0.53) F10F2KLKB1ELANE
SCHEMBL6589877 0.81 F10 (0.68) F10F2KLKB1ELANE
SCHEMBL27457200 0.78 F2 (0.44) F10F2KLKB1ELANE
SCHEMBL27455142 0.76 P2RX1 (0.47) F10F2KLKB1
SCHEMBL27550881 0.76 F10 (0.45) F10F2KLKB1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1143855-C I (ortho)-anthranilamide derivatives as anti-coagulants ���ֹɷݹ�˾ 2004-03-31 CN disclosed