Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454667 | 0.80 | PTGS1 (0.41) | GABRA1GABRB2PTGS1PTGS2MAPT | |
| SCHEMBL5692015 | 0.77 | GABRA1 (0.49) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9193416 | 0.74 | GABRA1 (0.54) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL5692077 | 0.74 | GABRA1 (0.54) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL27455835 | 0.74 | GABRA1 (0.46) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9195415 | 0.68 | GABRA1 (0.51) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL27471347 | 0.68 | PTGS1 (0.30) | PTGS1PTGS2 | |
| SCHEMBL27456868 | 0.68 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL13057520 | 0.65 | GSR (0.57) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9195024 | 0.65 | GABRA1 (0.51) | GABRA1GABRB1GABRB2GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147495-C | Alkyl-4-silyl heterocyclic phenols and thiophenols as antioxidants | ���µ�˹ҩ�﹫˾ | 2004-04-28 | — | — | CN | disclosed |
| CN-1261367-A | Alkyl-4-silylheterocyclic phenols and thiophenols as antioxidant agents | HOECHST MARION ROUSSEL INC (US) | 2000-07-26 | — | — | CN | disclosed |