Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | PPIG | Q13427 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459939 | 0.90 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDTSHRGLA | |
| SCHEMBL27792097 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRGLA | |
| SCHEMBL28394951 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDTSHRGLA | |
| SCHEMBL8905179 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDL3MBTL1RAB9A | |
| SCHEMBL8714848 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDPPIBPPID | |
| SCHEMBL25920678 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDGLARAB9A | |
| SCHEMBL27480557 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDGLARAB9A | |
| SCHEMBL29280745 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDL3MBTL1RAB9A | |
| SCHEMBL29280746 | 0.80 | ALDH1A1 (0.52) | ALDH1A1GLAL3MBTL1RAB9AMAOA | |
| SCHEMBL3084308 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDTSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800905-A | Preparation method of 4- (2, 6-dimethyl-3-nitropyridin-4-ylamino) phenethyl carbamic acid benzyl ester | 洛阳惠中兽药有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117800905-A | Preparation method of 4- (2, 6-dimethyl-3-nitropyridin-4-ylamino) phenethyl carbamic acid benzyl ester | 洛阳惠中兽药有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-101137656-B | Crystal forms of imidazole derivatives | PFIZER JAPAN INC | 2010-12-22 | — | — | CN | disclosed |
| CN-101137656-A | Crystal forms of imidazole derivatives | PFIZER JAPAN INC (US) | 2008-03-05 | — | — | CN | disclosed |
| CN-1149869-A | Substituted sulfonamides as selective beta3 agonists for treatment of diabetes and obesity | MERCK & CO LTD (US) | 1997-05-14 | — | — | CN | disclosed |