Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.67 |
| ▸ | ERAP1 | Q9NZ08 | 6/20 | 0.67 |
| ▸ | IL1RN | P18510 | 5/20 | 0.67 |
| ▸ | ECE1 | P42892 | 3/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.55 |
| ▸ | NMBR | P28336 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200899 | 0.83 | ERAP1 (0.67) | ERAP2ERAP1IL1RNECE1LNPEP | |
| SCHEMBL7305342 | 0.83 | ERAP1 (0.62) | ERAP2ERAP1IL1RNECE1LNPEP | |
| SCHEMBL7311262 | 0.82 | ERAP1 (0.75) | ERAP2ERAP1IL1RNECE1LNPEP | |
| SCHEMBL27887777 | 0.82 | ERAP2 (0.74) | ERAP2ERAP1IL1RNECE1LNPEP | |
| SCHEMBL9471355 | 0.81 | IL1RN (0.71) | ERAP2ERAP1IL1RNNMBRREN | |
| SCHEMBL9471350 | 0.81 | IL1RN (0.71) | ERAP2ERAP1IL1RNNMBRREN | |
| SCHEMBL8100241 | 0.81 | IL1RN (0.70) | ERAP2ERAP1IL1RNNMBRREN | |
| SCHEMBL27785997 | 0.81 | ERAP1 (0.72) | ERAP2ERAP1IL1RNECE1LNPEP | |
| SCHEMBL27785993 | 0.81 | ERAP1 (0.72) | ERAP2ERAP1IL1RNECE1LNPEP | |
| SCHEMBL16465069 | 0.80 | ERAP1 (0.71) | ERAP2ERAP1IL1RNECE1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120844-A | Phosphonomethyldipeptides | MERRELL DOW PHARMA (US) | 1996-04-17 | — | — | CN | disclosed |