Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 8/20 | 0.67 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.67 |
| ▸ | IL1RN | P18510 | 5/20 | 0.67 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MMP8 | P22894 | 2/20 | 0.57 |
| ▸ | MMP14 | P50281 | 2/20 | 0.57 |
| ▸ | MMP7 | P09237 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 5/20 | 0.55 |
| ▸ | NMBR | P28336 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313702 | 0.93 | ECE1 (0.61) | ERAP1ERAP2IL1RNECE1ANPEP | |
| SCHEMBL7313675 | 0.86 | ECE1 (0.61) | ERAP1ERAP2IL1RNECE1ANPEP | |
| SCHEMBL8908474 | 0.85 | ERAP2 (0.56) | ERAP1ERAP2IL1RNLNPEPMMP2 | |
| SCHEMBL7310121 | 0.84 | ERAP1 (0.63) | ERAP1ERAP2IL1RNLNPEPMMP2 | |
| SCHEMBL27435445 | 0.84 | IL1RN (0.55) | ERAP1ERAP2IL1RNMMP2ECE1 | |
| SCHEMBL27435446 | 0.84 | IL1RN (0.55) | ERAP1ERAP2IL1RNMMP2ECE1 | |
| SCHEMBL27458142 | 0.83 | ERAP2 (0.67) | ERAP1ERAP2IL1RNLNPEPMMP2 | |
| SCHEMBL7311262 | 0.82 | ERAP1 (0.75) | ERAP1ERAP2IL1RNLNPEPMMP2 | |
| SCHEMBL27887777 | 0.82 | ERAP2 (0.74) | ERAP1ERAP2IL1RNLNPEPMMP2 | |
| SCHEMBL7358374 | 0.81 | NMBR (0.61) | ERAP1ERAP2IL1RNLNPEPMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691985-B1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMA INC (US) | 2000-05-03 | — | — | EP | claimed |