SCHEMBL27458463

SCHEMBL27458463

C1=CCC2=Nc3ccccc3C2=C1.[H+]

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473567 0.98 IDO1 (0.31) IDO1
SCHEMBL272379 0.98 IDO1 (0.31) IDO1
SCHEMBL7707490 0.86 MEN1 (0.33)
SCHEMBL28599272 0.77
SCHEMBL27839465 0.72 ALDH1A1 (0.32)
SCHEMBL27987698 0.71 IDO1 (0.30) IDO1
SCHEMBL27970376 0.71 IDO1 (0.30) IDO1
SCHEMBL28165787 0.71 NISCH (0.34)
SCHEMBL30801318 0.70
SCHEMBL29059131 0.70 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1349417-A Contraceptive compositions containing 3,3-substituted indoline derivatives and use thereof AMERICAN HOME PROD (US) 2002-05-15 CN claimed
CN-1349500-A 3,3-substituted indoline derivatives AMERICAN HOME PROD (US) 2002-05-15 CN claimed
CN-105001226-A Tricycle heterocyclic compounds and JAK inhibitors NISSAN CHEMICAL IND LTD 2015-10-28 CN disclosed
CN-103732597-A Tricyclic heterocyclic compounds and JAK inhibitors NISSAN CHEMICAL IND LTD 2014-04-16 CN disclosed
CN-1125070-C Pyrrolo [2,3-d] pyrmidine compounds PFIZER PROD INC (US) 2003-10-22 CN disclosed
CN-1349417-A Contraceptive compositions containing 3,3-substituted indoline derivatives and use thereof AMERICAN HOME PROD (US) 2002-05-15 CN disclosed
CN-1349500-A 3,3-substituted indoline derivatives AMERICAN HOME PROD (US) 2002-05-15 CN disclosed
CN-1305479-A Pyrrolo [2,3-d] pyrmidine compounds PFIZER PROD INC (US) 2001-07-25 CN disclosed