Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095889 | 0.78 | HTR6 (0.61) | HTR6 | |
| SCHEMBL9095892 | 0.78 | HTR6 (0.61) | HTR6 | |
| SCHEMBL12303279 | 0.76 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3324500 | 0.74 | HTR6 (1.00) | HTR6 | |
| SCHEMBL1751004 | 0.74 | HTR6 (0.60) | HTR6 | |
| SCHEMBL9959652 | 0.68 | HTR6 (0.44) | HTR6 | |
| SCHEMBL9959779 | 0.68 | HTR6 (0.54) | HTR6 | |
| SCHEMBL12303254 | 0.66 | HTR6 (0.46) | HTR6 | |
| SCHEMBL22455764 | 0.66 | HTR6 (0.55) | HTR6 | |
| SCHEMBL7104625 | 0.65 | HTR1B (0.65) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1515252-A | Application of indole derivative as SHTI excitomotor | — | 2004-07-28 | — | — | CN | claimed |
| CN-1121689-A | Use of indole derivatives as 5HT1 antagonists | PFIZER (US) | 1996-05-01 | — | — | CN | claimed |