Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473755 | 0.79 | TDP1 (1.00) | TDP1DAOMEN1KMT2APOLB | |
| SCHEMBL3511878 | 0.79 | TDP1 (0.64) | TDP1DAOMEN1KMT2ATAAR1 | |
| SCHEMBL27815837 | 0.78 | TDP1 (0.61) | TDP1DAOMEN1KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL11749926 | 0.75 | TDP1 (0.42) | TDP1DAOMEN1KMT2AGSK3A | |
| SCHEMBL27433357 | 0.74 | IDO1 (0.49) | TDP1MEN1KMT2AGSK3AGSK3B | |
| SCHEMBL9326774 | 0.74 | ALDH1A1 (0.68) | TDP1MEN1KMT2APOLB | |
| SCHEMBL10536673 | 0.74 | ALDH1A1 (0.68) | TDP1MEN1KMT2APOLB | |
| SCHEMBL8873673 | 0.74 | ALDH1A1 (0.68) | TDP1MEN1KMT2APOLB | |
| SCHEMBL29611880 | 0.74 | KMT2A (0.69) | TDP1MEN1KMT2ATAAR1SLC6A2 | |
| SCHEMBL3707839 | 0.73 | KMT2A (0.57) | TDP1DAOMEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125448-A | 14-substituted marcfortines and derivatives useful as antiparasitic agents | UPJOHN CO (US) | 1996-06-26 | — | — | CN | claimed |
| CN-1125448-A | 14-substituted marcfortines and derivatives useful as antiparasitic agents | UPJOHN CO (US) | 1996-06-26 | — | — | CN | disclosed |