Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 17/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512005 | 0.90 | OPRD1 (0.82) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27485227 | 0.88 | OPRD1 (0.79) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6797795 | 0.88 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27458260 | 0.87 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27551286 | 0.87 | OPRD1 (0.78) | OPRD1OPRM1OPRK1ABCB11KCNH2 | |
| SCHEMBL27476086 | 0.84 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27473306 | 0.83 | OPRD1 (0.73) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27501405 | 0.82 | OPRD1 (0.80) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27476085 | 0.82 | OPRD1 (0.80) | OPRD1OPRM1OPRK1ABCB11KCNH2 | |
| SCHEMBL27474131 | 0.81 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100519528-C | Compounds with analgesic effect | ASTRA PHARMACEUTICALS INC (CA) | 2009-07-29 | — | — | CN | disclosed |
| CN-1524852-A | Novel compounds with analgesic effect | ������ҩ������˾ | 2004-09-01 | — | — | CN | disclosed |
| CN-1146540-C | Novel compound with analgesic effect and application thereof | ������ҩ������˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1246111-A | Novel compound with analgesic effect | ASTRA PHARMA INC (CA) | 2000-03-01 | — | — | CN | disclosed |