Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587031 | 0.80 | ADRB3 (0.50) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8587028 | 0.80 | ADRB3 (0.50) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8794361 | 0.79 | ADRB3 (0.46) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL24307676 | 0.73 | ADRB3 (0.37) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL15275450 | 0.73 | ADRB3 (0.76) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL9683368 | 0.71 | ADRB3 (0.74) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL9683373 | 0.71 | ADRB3 (0.74) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7116296 | 0.71 | ADRB3 (0.79) | ADRB3ADRB1ADRB2KMT2AALDH1A1 | |
| SCHEMBL15445682 | 0.71 | KMT2A (0.71) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL30206978 | 0.71 | PREP (0.41) | ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159797-A | Aryloxy and arylthiopropanolamine derivative suseful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof | SMITHKLINE BEECHAM PLC (GB) | 1997-09-17 | — | — | CN | disclosed |