Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683368 | 1.00 | ADRB3 (0.74) | ADRB3ADRB1ADRB2MEN1MAPT | |
| SCHEMBL7122769 | 0.94 | ADRB3 (0.76) | ADRB3ADRB1ADRB2MEN1MAPT | |
| SCHEMBL15275450 | 0.91 | ADRB3 (0.76) | ADRB3ADRB1ADRB2MEN1MAPT | |
| SCHEMBL27478454 | 0.91 | ADRB1 (0.78) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9683296 | 0.89 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9330198 | 0.89 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7119163 | 0.88 | ADRB3 (0.79) | ADRB3ADRB1ADRB2 | |
| SCHEMBL18651970 | 0.88 | ADRB3 (0.79) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9817936 | 0.88 | ADRB1 (0.73) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9332316 | 0.87 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |