Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 17/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475512 | 0.89 | PGR (0.53) | PGRPARP10PARP11 | |
| SCHEMBL27551501 | 0.85 | PGR (0.55) | PGR | |
| SCHEMBL6770129 | 0.83 | PGR (0.61) | PGRPARP10PARP11 | |
| SCHEMBL27501214 | 0.77 | PGR (0.70) | PGR | |
| SCHEMBL27472979 | 0.74 | PGR (0.53) | PGR | |
| SCHEMBL6777083 | 0.74 | PGR (0.60) | PGR | |
| SCHEMBL6772564 | 0.71 | PGR (0.67) | PGRPARP10PARP11 | |
| SCHEMBL6767320 | 0.70 | PGR (1.00) | PGR | |
| SCHEMBL27456113 | 0.69 | PGR (0.70) | PGR | |
| SCHEMBL4906094 | 0.68 | PGR (0.81) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1145610-C | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators | 美国家庭用品有限公司 | 2004-04-14 | — | — | CN | disclosed |
| CN-1349508-A | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349413-A | Contraceptive compositions containing quinazolinone and benzoxazine derivatives | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |