Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.63 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650532 | 1.00 | ITGB3 (0.63) | ITGB3ITGA2BPREPFAPCA2 | |
| SCHEMBL5144245 | 0.86 | ITGB3 (0.71) | ITGB3ITGA2BPREPFAPSMYD3 | |
| SCHEMBL4434863 | 0.86 | ITGB3 (0.71) | ITGB3ITGA2BPREPFAPSMYD3 | |
| SCHEMBL8649064 | 0.86 | ITGB3 (0.71) | ITGB3ITGA2BPREPFAPSMYD3 | |
| SCHEMBL8648337 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL8647567 | 0.81 | MEN1 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8377742 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL8648096 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2BPREPFAPSMYD3 | |
| SCHEMBL27402980 | 0.78 | ITGB3 (0.52) | ITGB3ITGA2BCA2CA1 | |
| SCHEMBL24336750 | 0.78 | ITGB3 (0.72) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | claimed |
| CN-1075062-C | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | CN | disclosed |
| CN-1112104-A | Acetic acid derivatives | HOFFMANN LA ROCHE (CH) | 1995-11-22 | — | — | CN | disclosed |