Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.43 |
| ▸ | RARG | P13631 | 7/20 | 0.43 |
| ▸ | RARA | P10276 | 6/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FABP1 | P07148 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479688 | 0.89 | RARA (0.59) | RARBRARGRARAALDH1A1KMT2A | |
| SCHEMBL8771867 | 0.74 | RARB (0.46) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL17275573 | 0.71 | RARB (0.50) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8771650 | 0.68 | RARB (0.77) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8771633 | 0.67 | RARA (0.66) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL12365222 | 0.66 | TDP1 (0.44) | RARBRARGRARATTRPTPRC | |
| SCHEMBL4653413 | 0.63 | RARA (0.71) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8149892 | 0.62 | PTPRC (0.66) | TTRPTPRCKMOALDH1A1KMT2A | |
| SCHEMBL36018 | 0.62 | TTR (0.62) | TTRPTPRCKMOALDH1A1KMT2A | |
| SCHEMBL8771689 | 0.62 | PDK2 (0.49) | RARBRARGRARARXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144217-A | Retinoid-like compounds | BRISTOL MYERS SQUIBB CO (US) | 1997-03-05 | — | — | CN | disclosed |