Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445011 | 0.80 | ACE (0.51) | ACE | |
| SCHEMBL5847068 | 0.79 | ACE (0.54) | ACE | |
| SCHEMBL5847071 | 0.79 | ACE (0.54) | ACE | |
| SCHEMBL27439563 | 0.79 | ACE (0.50) | ACE | |
| SCHEMBL17461305 | 0.79 | ACE (0.50) | ACE | |
| SCHEMBL10339439 | 0.79 | ACE (0.50) | ACE | |
| SCHEMBL4278365 | 0.79 | ACE (0.54) | ACE | |
| SCHEMBL29443075 | 0.79 | ACE (0.61) | ACE | |
| SCHEMBL8633111 | 0.79 | ACE (0.61) | ACE | |
| SCHEMBL27924667 | 0.79 | ACE (0.50) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628621-A | Method for preparing fluoro-substituted indol derivative | Hunan huateng pharmaceutical co ltd | 2015-05-20 | — | — | CN | claimed |
| CN-105254557-A | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RAQUALIA PHARMA INC | 2016-01-20 | — | — | CN | disclosed |
| CN-105143200-A | Serine/threonine kinase inhibitors for the treatment of hyperproliferative|diseases | ARRAY BIOPHARMA INC | 2015-12-09 | — | — | CN | disclosed |
| CN-105130957-A | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RAQUALIA PHARMA INC | 2015-12-09 | — | — | CN | disclosed |
| CN-102741222-B | Haloalkyl-substituted amides as insecticides and acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-02 | — | — | CN | disclosed |
| CN-102884059-B | N-acyl cyclic amine derivatives or pharmaceutically acceptable salts thereof | DAINIPPON SUMITOMO PHARMA CO.,LTD. (JP) | 2015-08-26 | — | — | CN | disclosed |
| CN-104628621-A | Method for preparing fluoro-substituted indol derivative | Hunan huateng pharmaceutical co ltd | 2015-05-20 | — | — | CN | disclosed |
| CN-103201276-B | Indole derivatives | RICHTER GEDEON NYRT | 2015-02-25 | — | — | CN | disclosed |
| CN-103992326-A | Indol-hexahydropyrazine-quinazolinone anti-tumour compounds and preparation method thereof | UNIV PLA 2ND MILITARY MEDICAL | 2014-08-20 | — | — | CN | disclosed |
| CN-103201276-A | Indole derivatives | RICHTER GEDEON NYRT | 2013-07-10 | — | — | CN | disclosed |
| CN-102884059-A | N-acyl cyclic amine derivatives or pharmaceutically acceptable salts thereof | DAINIPPON SUMITOMO PHARMA CO | 2013-01-16 | — | — | CN | disclosed |
| CN-101501053-B | 1- (-D-glucopyranosyl) -3- (4-cyclopropylphenylmethyl) -4-haloindole derivatives and their use as SGLT inhibitors | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101501053-A | 1- (-D-glucopyranosyl) -3- (4-cyclopropylphenylmethyl) -4-haloindole derivatives and their use as SGLT inhibitors | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-101151245-A | Indan-amide derivatives with glycogen phosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | CN | disclosed |
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | disclosed |