Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27563667 | 0.83 | ACE (0.52) | ACE | |
| SCHEMBL8208215 | 0.80 | DRD2 (0.50) | — | |
| SCHEMBL1445011 | 0.80 | ACE (0.51) | ACE | |
| SCHEMBL11077397 | 0.79 | ACE (0.58) | ACE | |
| SCHEMBL17461305 | 0.79 | ACE (0.50) | ACE | |
| SCHEMBL8633111 | 0.79 | ACE (0.61) | ACE | |
| SCHEMBL29443075 | 0.79 | ACE (0.61) | ACE | |
| SCHEMBL5847071 | 0.79 | ACE (0.54) | ACE | |
| SCHEMBL5847068 | 0.79 | ACE (0.54) | ACE | |
| SCHEMBL4278365 | 0.79 | ACE (0.54) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102143961-B | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2014-11-05 | — | — | CN | claimed |
| CN-102143961-A | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2011-08-03 | — | — | CN | claimed |
| CN-1283615-A | New Process and intermediate | PFIZER PROD INC (US) | 2001-02-14 | — | — | CN | claimed |
| CN-104254519-B | Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing the same as the active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-04-20 | — | — | CN | disclosed |
| CN-105073783-A | Pharmaceutical compositions with enhanced properties and improved processability | HERCULES INC | 2015-11-18 | — | — | CN | disclosed |
| CN-103201276-B | Indole derivatives | RICHTER GEDEON NYRT | 2015-02-25 | — | — | CN | disclosed |
| CN-104254519-A | Novel beta-alanine derivative, pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient | KOREA RES INST CHEM TECH | 2014-12-31 | — | — | CN | disclosed |
| CN-101247853-B | Substituted indole compounds having NOS inhibitory activity | NEURAXON INC | 2014-11-12 | — | — | CN | disclosed |
| CN-102143961-B | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2014-11-05 | — | — | CN | disclosed |
| CN-103992326-A | Indol-hexahydropyrazine-quinazolinone anti-tumour compounds and preparation method thereof | UNIV PLA 2ND MILITARY MEDICAL | 2014-08-20 | — | — | CN | disclosed |
| CN-103906756-A | Methods for treating diseases | GALERA THERAPEUTICS LLC | 2014-07-02 | — | — | CN | disclosed |
| CN-1636991-A | Sodium-hydrogen exchanger type 1 inhibitor crystals | PFIZER PROD INC (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1205205-C | sodium-hydrogen exchanger type 1 inhibitor crystal | PFIZER PROD INC (US) | 2005-06-08 | — | — | CN | disclosed |
| CN-1098838-C | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1384829-A | sodium-hydrogen exchanger type 1 inhibitor crystal | PFIZER PROD INC (US) | 2002-12-11 | — | — | CN | disclosed |
| CN-1374967-A | Compounds for the treatment of ischemia | PFIZER PROD INC (US) | 2002-10-16 | — | — | CN | disclosed |
| CN-1283615-A | New Process and intermediate | PFIZER PROD INC (US) | 2001-02-14 | — | — | CN | disclosed |
| CN-1283186-A | Indole derivatives as XA factor inhibitors | AWENTIS MEDICINES DEUTSCHLAND (DE) | 2001-02-07 | — | — | CN | disclosed |
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | disclosed |
| CN-1140709-A | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 1997-01-22 | — | — | CN | disclosed |