SCHEMBL27463258

SCHEMBL27463258

CC(C)CN(CC(O)C(=O)OCc1ccccc1)C(=O)NC(Cc1ccc(-c2cccc3ccccc23)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MME P08473 12/20 0.64
ACE P12821 12/20 0.64
PPARG P37231 4/20 0.45
PPARA Q07869 3/20 0.45
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8030383 1.00 MME (0.64) MMEACEPPARGPPARAMEN1
SCHEMBL27441332 0.96 MME (0.57) MMEACEPPARGPPARAMEN1
SCHEMBL27441356 0.93 MME (0.55) MMEACEPPARGPPARA
SCHEMBL27441357 0.93 MME (0.55) MMEACEPPARGPPARA
SCHEMBL27464917 0.93 MME (0.54) MMEACEPPARGPPARAMEN1
SCHEMBL8027268 0.92 MME (0.65) MMEACEPPARGPPARA
SCHEMBL8027409 0.91 ACE (0.52) MMEACEPPARGPPARAMEN1
SCHEMBL8027420 0.91 MME (0.77) MMEACEPPARGPPARAMEN1
SCHEMBL7568400 0.89 MME (0.52) MMEACEPPARGPPARAMEN1
SCHEMBL7568408 0.89 MME (0.52) MMEACEPPARGPPARAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1138321-A 1, 3-dialkyl urea derivative with hydrocarbon group SANTAN PHARMACEUTICAL CO LTD (JP) 1996-12-18 CN disclosed