SCHEMBL27463264

SCHEMBL27463264

CC(C)(C)c1cc[c]cc1.O[AlH2]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
TSHR P16473 1/20 0.42
KIF11 P52732 2/20 0.37
HDAC1 Q13547 1/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
BCHE P06276 5/20 0.36
ACHE P22303 5/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SRD5A2 P31213 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CYP1A2 P05177 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28104416 0.92 TSHR (0.48) LMNATYRTSHRKIF11HDAC1
SCHEMBL21735 0.92 TSHR (0.48) LMNATYRTSHRKIF11HDAC1
SCHEMBL27497107 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL27420151 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL27962246 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL27719194 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL27389069 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL27344926 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL27371242 0.89 TSHR (0.46) LMNATYRTSHRKIF11HDAC1
SCHEMBL28869048 0.87 LMNA (0.44) LMNATYRTSHRKIF11HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1119364-C Propylene ethylene copolymer compositions and process for the production thereof CHISSO CORP (JP) 2003-08-27 CN disclosed
CN-1169743-A Propylene-ethylene copolymer composition and process for producing the same CHISSO CORP (JP) 1998-01-07 CN disclosed