Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.69 |
| ▸ | EGFR | P00533 | 5/20 | 0.69 |
| ▸ | KDR | P35968 | 10/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.62 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28198357 | 0.85 | KDR (0.64) | MAPK14EGFRKDRAURKAAURKB | |
| SCHEMBL6786328 | 0.85 | EGFR (0.77) | MAPK14EGFRKDRSRC | |
| SCHEMBL29220499 | 0.85 | AURKB (0.79) | MAPK14EGFRKDRAURKAAURKB | |
| SCHEMBL27718809 | 0.84 | KDR (0.81) | MAPK14EGFRKDRAURKAAURKB | |
| SCHEMBL5485308 | 0.83 | EGFR (0.77) | MAPK14EGFRKDRAURKAAURKB | |
| Hydrochloric Acid SCHEMBL5471735 | 0.82 | EGFR (0.75) | MAPK14EGFRKDRSRC | |
| SCHEMBL23075143 | 0.82 | KDR (0.62) | EGFRKDRAURKAAURKBSRC | |
| SCHEMBL6785711 | 0.82 | MAPK14 (1.00) | MAPK14EGFRKDRAURKAAURKB | |
| Hydrochloric Acid SCHEMBL27479012 | 0.82 | CLK1 (0.63) | MAPK14EGFRKDR | |
| Hydrochloric Acid SCHEMBL6794010 | 0.81 | MAPK14 (0.81) | MAPK14EGFRKDRAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158266-C | Chemical compounds | — | 2004-07-21 | — | — | CN | claimed |
| CN-1321151-A | Chemical compounds | ASTRAZENECA AB (SE) | 2001-11-07 | — | — | CN | claimed |
| CN-1158266-C | Chemical compounds | — | 2004-07-21 | — | — | CN | disclosed |
| CN-1321151-A | Chemical compounds | ASTRAZENECA AB (SE) | 2001-11-07 | — | — | CN | disclosed |