Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.64 |
| ▸ | FLT1 | P17948 | 2/20 | 0.64 |
| ▸ | RET | P07949 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.64 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.64 |
| ▸ | KIF5B | P33176 | 1/20 | 0.64 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.64 |
| ▸ | EGFR | P00533 | 4/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.63 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220499 | 0.88 | AURKB (0.79) | KDRRETMAPK14EGFRAURKB | |
| SCHEMBL27718809 | 0.87 | KDR (0.81) | KDRMAPK14EGFRAURKBAURKA | |
| SCHEMBL27793599 | 0.87 | KDR (0.65) | KDRRETKIF5BMAPK14EGFR | |
| Hydrochloric Acid SCHEMBL27587585 | 0.86 | EGFR (0.66) | KDRRETKIF5BMAPK14EGFR | |
| SCHEMBL27463430 | 0.85 | MAPK14 (0.69) | KDRMAPK14EGFRAURKBAURKA | |
| Hydrochloric Acid SCHEMBL28040048 | 0.81 | AURKB (0.58) | KDRRETEPHB2KIF5BMAPK14 | |
| Hydrochloric Acid SCHEMBL27451004 | 0.81 | KDR (0.67) | KDRRETKIF5BMAPK14EGFR | |
| SCHEMBL27433932 | 0.81 | EGFR (0.62) | KDRMAPK14EGFRAURKBAURKA | |
| SCHEMBL30249695 | 0.78 | KDR (1.00) | KDRFGFR1FLT1RETCDK2 | |
| SCHEMBL1180103 | 0.78 | KDR (1.00) | KDRFGFR1FLT1RETCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272291-B | Differentiation of human embryonic stem cells into the pancreatic endocrine lineage | 詹森生物科技公司 | 2018-01-16 | — | — | CN | claimed |