Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL27463519

N#CCCOP(N)O.N#CCCOP(N)O.S

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LOX P28300 1/20 0.32
LOXL3 P58215 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55354 0.98
SCHEMBL9436380 0.98
Hydrochloric Acid SCHEMBL17225016 0.95
Acetonitrile SCHEMBL3230174 0.91
Hexaethylene Glycol SCHEMBL7046764 0.84 MEN1 (0.41)
SCHEMBL30259800 0.82
SCHEMBL30148034 0.82 GAA (0.33)
SCHEMBL55353 0.77 ALDH1A1 (0.37) LOXLOXL3LOXL2ALDH1A1TDP1
SCHEMBL10344679 0.77 ALDH1A1 (0.37) LOXLOXL3LOXL2ALDH1A1TDP1
SCHEMBL16656334 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1120707-C Ligands to enhance cellular uptake of biomolecules UNIV JOHNS HOPKINS (US) 2003-09-10 CN disclosed
CN-1211923-A Ligands that enhance cellular uptake of biomolecules UNIV JOHNS HOPKINS (US) 1999-03-24 CN disclosed