Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480789 | 0.94 | ACAT1 (0.61) | ACAT1SOAT1PDE4APDE4BPDE4C | |
| SCHEMBL27463675 | 0.93 | ACAT1 (0.53) | ACAT1SOAT1PDE4APDE4BPDE4C | |
| SCHEMBL27483049 | 0.93 | ACAT1 (0.54) | ACAT1SOAT1ALDH1A1 | |
| SCHEMBL27482662 | 0.89 | ACAT1 (0.53) | ACAT1SOAT1PDE4APDE4BPDE4C | |
| SCHEMBL27570663 | 0.88 | ACAT1 (0.49) | ACAT1SOAT1ALDH1A1 | |
| SCHEMBL27464491 | 0.88 | ACAT1 (0.50) | ACAT1SOAT1 | |
| SCHEMBL27464492 | 0.88 | ACAT1 (0.52) | ACAT1SOAT1 | |
| SCHEMBL27482312 | 0.88 | ACAT1 (0.50) | ACAT1SOAT1 | |
| SCHEMBL27483391 | 0.88 | ACAT1 (0.50) | ACAT1SOAT1 | |
| Piperidine SCHEMBL27464493 | 0.87 | ACAT1 (0.51) | ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152879-C | Naphthyridine derivatives | ס����ҩ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1323306-A | Naphthyridine derivatives | SUMITOMO PHARMA (JP) | 2001-11-21 | — | — | CN | disclosed |