Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL7264826 | 1.00 | TSHR (0.56) | TSHRFFAR3TP53ALOX15BLM | |
| Lactic Acid SCHEMBL11340701 | 0.83 | TP53 (0.61) | FFAR3TP53ALOX15BLMPMP22 | |
| Cadaverine Tartrate SCHEMBL5874700 | 0.82 | TSHR (0.62) | TSHRTP53BLMPMP22CYP2C9 | |
| Cadaverine Tartrate SCHEMBL1468444 | 0.82 | TSHR (0.62) | TSHRFFAR3TP53CYP2C9PDE4A | |
| Cadaverine Tartrate SCHEMBL5874705 | 0.82 | TSHR (0.62) | TSHRTP53BLMPMP22CYP2C9 | |
| Tartaric Acid SCHEMBL30628132 | 0.82 | TSHR (0.62) | TSHRTP53BLMPMP22CYP2C9 | |
| Cadaverine Tartrate SCHEMBL28281421 | 0.82 | TSHR (0.48) | TSHRFFAR3TP53ALOX15BLM | |
| Cadaverine Tartrate SCHEMBL28281422 | 0.82 | TSHR (0.48) | TSHRFFAR3TP53ALOX15BLM | |
| Cadaverine Tartrate SCHEMBL18987140 | 0.82 | TSHR (0.71) | TSHRFFAR3TP53CYP2C9PDE4A | |
| Propionamide SCHEMBL4230074 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310664-A | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | 田纳西大学研究基金会 | 2019-02-05 | — | — | CN | disclosed |
| CN-1152049-C | Treatment of insulin resistance with growth hormone secretagogues | �Ʒ� | 2004-06-02 | — | — | CN | disclosed |