Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219892 | 0.95 | TSHR (0.61) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28290465 | 0.90 | ALDH1A1 (0.58) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| Methyl Alcohol SCHEMBL27495118 | 0.88 | TSHR (0.70) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL1513967 | 0.88 | TSHR (0.69) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28853026 | 0.86 | TSHR (0.63) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL5416441 | 0.85 | TSHR (0.54) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL27562850 | 0.84 | TSHR (0.43) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL27864832 | 0.83 | TSHR (0.72) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL27777690 | 0.83 | ALDH1A1 (0.79) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL873755 | 0.83 | TSHR (0.64) | TSHRTDP1L3MBTL1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108367008-A | Pharmaceutical composition comprising doramevirine, tenofovir disoproxil fumarate and lamivudine | 默沙东公司 | 2018-08-03 | — | — | CN | claimed |
| CN-103735515-A | Polymer formulations of cetp inhibitors | MERCK & CO INC | 2014-04-23 | — | — | CN | claimed |
| CN-1859909-B | Solid dispersions comprising tacrolimus | LIFECYCLE PHARMA AS | 2011-04-06 | — | — | CN | claimed |
| CN-101869561-A | The improvement release composition that contains tacrolimus | LIFECYCLE PHARMA AS | 2010-10-27 | — | — | CN | claimed |
| CN-101652141-A | The adjustment release dosage form of tacrolimus | PANACEA BIOTEC LTD IN | 2010-02-17 | — | — | CN | claimed |
| CN-101378731-A | Polymer formulations of CETP inhibitors | MERCK & CO INC (US) | 2009-03-04 | — | — | CN | claimed |
| CN-1859910-A | Modified release composition containing tacrolimus | LIFECYCLE PHARMA AS (DK) | 2006-11-08 | — | — | CN | claimed |
| CN-1859909-A | Solid dispersions comprising tacrolimus | LIFECYCLE PHARMA AS (DK) | 2006-11-08 | — | — | CN | claimed |
| CN-1212832-C | Soft capsule containing vinyl ester and poly ether polymer, its use and producing method | BASF AG (DE) | 2005-08-03 | — | — | CN | claimed |
| CN-1571658-A | Pharmaceutical formulations comprising -bicalutamide | ASTRAZENECA UK LTD (GB) | 2005-01-26 | — | — | CN | claimed |
| CN-1326732-A | Soft capsule containing vinyl ester and poly ether polymer, its use and producing method | BASF AG (DE) | 2001-12-19 | — | — | CN | claimed |
| CN-1094948-A | Controlled release device | GLAXO CANADA (CA) | 1994-11-16 | — | — | CN | claimed |
| CN-110494142-A | Treatment of cancer | GILLIES MCINDOE RES INSTITUTE | 2019-11-22 | — | — | CN | disclosed |
| CN-109897004-A | The miscellaneous Shandong amine preparation of grace | 麦迪威森前列腺医疗有限责任公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109674795-A | Itraconazole composition and dosage form and its application method | 梅恩医药国际有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109563176-A | Cellulose acetate phthalate ether | 陶氏环球技术有限责任公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-1625389-A | Method for preparing a homogeneous spray-dried solid amorphous drug dispersion using an improved spray-drying apparatus | PFIZER (US) | 2005-06-08 | — | — | CN | disclosed |
| CN-1571658-A | Pharmaceutical formulations comprising -bicalutamide | ASTRAZENECA UK LTD (GB) | 2005-01-26 | — | — | CN | disclosed |
| CN-1474686-A | Hydrolytically unstable compositions | 弗・哈夫曼-拉罗切有限公司 | 2004-02-11 | — | — | CN | disclosed |
| CN-1326732-A | Soft capsule containing vinyl ester and poly ether polymer, its use and producing method | BASF AG (DE) | 2001-12-19 | — | — | CN | disclosed |