Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31126834 | 0.89 | KDM4E (0.68) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL2860044 | 0.89 | KDM4E (0.68) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL4474267 | 0.88 | CYP1A2 (0.74) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11370286 | 0.85 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11421007 | 0.84 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL27451251 | 0.84 | KMT2A (0.56) | KMT2ASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL19805148 | 0.83 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10489819 | 0.83 | KMT2A (0.63) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL28401182 | 0.82 | ALDH1A1 (0.72) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL10807728 | 0.81 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137271-A | 4-benzoylisoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-12-04 | — | — | CN | disclosed |