SCHEMBL27465271

SCHEMBL27465271

Cc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
PTGER4 P35408 1/20 0.39
TSPO P30536 1/20 0.38
ALDH1A1 P00352 6/20 0.38
RXFP1 Q9HBX9 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
GAA P10253 3/20 0.36
GFER P55789 1/20 0.36
LMNA P02545 3/20 0.36
HTT P42858 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 3/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928046 1.00 KDM4E (0.49) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL13725850 1.00 KDM4E (0.49) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL8928125 1.00 KDM4E (0.49) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL25937133 0.99 L3MBTL1 (0.47) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL13157273 0.99 KDM4E (0.47) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL13725005 0.96 KDM4E (0.44) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL25630825 0.96 KDM4E (0.44) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL13724932 0.96 KDM4E (0.44) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL13725885 0.96 KDM4E (0.42) KDM4EATML3MBTL1AKR1C4AKR1C3
SCHEMBL8928071 0.96 KDM4E (0.53) KDM4EATML3MBTL1PTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395497-A1 LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed