Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OGG1 | O15527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28463146 | 0.79 | KDM4E (0.46) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL27922560 | 0.77 | KDM4E (0.50) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL4148560 | 0.77 | CTSD (0.50) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL4409617 | 0.75 | GAA (0.57) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL4409987 | 0.73 | GAA (0.55) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL9183915 | 0.73 | — | — | |
| SCHEMBL4414727 | 0.73 | GAA (0.55) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL25002949 | 0.73 | — | — | |
| SCHEMBL10874948 | 0.72 | TSHR (0.52) | KDM4ECTSDKDM5CPHF8KDM2A | |
| SCHEMBL8676336 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155573-C | Fluorescent reagent 2-(N-carbazyl)-chlorethyl formate | 中国科学院大连化学物理研究所 | 2004-06-30 | — | — | CN | claimed |
| CN-1357540-A | Fluorescent reagent 2-(N-carbazyl)-chlorethyl formate | DALIAN CHEMICAL PHYSICS INST (CN) | 2002-07-10 | — | — | CN | claimed |
| CN-100412060-C | Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide | DALIAN CHEMICAL PHYSICS INST (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-1810789-A | Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide | DALIAN CHEMICAL PHYSICS INST (CN) | 2006-08-02 | — | — | CN | disclosed |
| CN-1155573-C | Fluorescent reagent 2-(N-carbazyl)-chlorethyl formate | 中国科学院大连化学物理研究所 | 2004-06-30 | — | — | CN | disclosed |
| CN-1357540-A | Fluorescent reagent 2-(N-carbazyl)-chlorethyl formate | DALIAN CHEMICAL PHYSICS INST (CN) | 2002-07-10 | — | — | CN | disclosed |