Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.42 |
| ▸ | FNTB | P49356 | 16/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599149 | 0.82 | FNTA (0.57) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6610933 | 0.80 | FNTA (0.48) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6599647 | 0.79 | FNTA (0.50) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6599682 | 0.77 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6599130 | 0.77 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6607574 | 0.77 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL27508283 | 0.77 | FNTA (0.61) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6609102 | 0.77 | FNTA (0.43) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL27481888 | 0.76 | FNTA (0.63) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL27497640 | 0.76 | FNTA (0.73) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151148-C | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LGCI��ʽ���� | 2004-05-26 | — | — | CN | claimed |
| CN-1346353-A | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LG CHEMICAL LTD (KR) | 2002-04-24 | — | — | CN | claimed |
| CN-1151148-C | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LGCI��ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| CN-1346353-A | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LG CHEMICAL LTD (KR) | 2002-04-24 | — | — | CN | disclosed |