Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.51 |
| ▸ | PRCP | P42785 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334819 | 0.87 | SMN1; SMN2 (0.57) | OPRM1PRCPOPRK1SMN1; SMN2SLC22A1 | |
| Hydrochloric Acid SCHEMBL8470673 | 0.86 | SMN1; SMN2 (0.56) | OPRM1PRCPOPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL16204777 | 0.83 | OPRM1 (0.43) | OPRM1OPRK1 | |
| SCHEMBL18586033 | 0.80 | OPRM1 (0.54) | OPRM1PRCPOPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL18586549 | 0.80 | OPRM1 (0.54) | OPRM1PRCPOPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL23119015 | 0.79 | TSHR (0.60) | OPRM1PRCPOPRK1SMN1; SMN2 | |
| SCHEMBL4853532 | 0.79 | TSHR (0.60) | OPRM1PRCPOPRK1SMN1; SMN2 | |
| SCHEMBL8682853 | 0.78 | PRCP (0.41) | OPRM1PRCPOPRK1 | |
| Hydrochloric Acid SCHEMBL19953531 | 0.77 | TSHR (0.62) | OPRM1PRCPOPRK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2790413 | 0.77 | TSHR (0.62) | OPRM1PRCPOPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167485-A | Tetrahydroisoquinoline derivative and medicinal preparation containing the same | TERUMO CORP (JP) | 1997-12-10 | — | — | CN | disclosed |