Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706011 | 0.87 | KMT2A (0.50) | LMNAKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL2479864 | 0.86 | TSHR (0.51) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| SCHEMBL27850860 | 0.85 | HCRTR1 (0.47) | TSHRHSD17B10L3MBTL1GLAKMT2A | |
| SCHEMBL27926910 | 0.83 | HCRTR1 (0.50) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| SCHEMBL16960258 | 0.82 | HPGD (0.44) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| Benzene SCHEMBL27314454 | 0.82 | ALDH1A1 (0.65) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| SCHEMBL124831 | 0.82 | ALDH1A1 (0.65) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| SCHEMBL539003 | 0.81 | KLK1 (0.52) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| SCHEMBL2345074 | 0.81 | PTGER1 (0.52) | TSHRHSD17B10L3MBTL1LMNAGLA | |
| SCHEMBL29768766 | 0.81 | MAPK1 (0.53) | TSHRHSD17B10L3MBTL1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189373-B | The Triazolopyridine replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-06 | — | — | CN | disclosed |
| CN-103608350-B | Triazolopyridine compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-102753547-B | Triazolopyridine derivatives | BAYER IP GMBH | 2015-06-03 | — | — | CN | disclosed |
| CN-103608350-A | Triazolopyridine compounds | BAYER IP GMBH | 2014-02-26 | — | — | CN | disclosed |
| CN-103189373-A | Substituted triazolopyridines | BAYER IP GMBH | 2013-07-03 | — | — | CN | disclosed |
| CN-1137271-A | 4-benzoylisoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-12-04 | — | — | CN | disclosed |