SCHEMBL27465876

SCHEMBL27465876

Fc1cc(F)c(S(I)(c2ccccc2)c2ccccc2)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.35
HTR2C P28335 2/20 0.35
KCNH2 Q12809 2/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
PKM P14618 1/20 0.32
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26035876 0.75 HTR2A (0.35) HTR2AHTR2CKCNH2CA12CA1
SCHEMBL777912 0.75 CA12 (0.53) HTR2AHTR2CKCNH2MEN1KMT2A
SCHEMBL19621137 0.71 HTR6 (0.47) MEN1KMT2ACA12CA1CA2
SCHEMBL27907856 0.67 HTR6 (0.39) CA12CA1CA2CA7CA13
SCHEMBL28334145 0.67 HTR6 (0.39) CA12CA1CA2CA7CA13
SCHEMBL4124405 0.63 TDP1 (0.44) HTR2AHTR2CKCNH2MEN1KMT2A
SCHEMBL27344463 0.61 CA1 (0.42) MEN1KMT2ACA1CA2CA7
SCHEMBL25097675 0.61 GBA1 (0.38) HTR2AHTR2CKCNH2MEN1KMT2A
SCHEMBL776403 0.61 HTR6 (0.64) HTR2AHTR2CKCNH2CA12CA1
SCHEMBL1265371 0.61 CYP1A2 (0.34) HTR2AHTR2CKCNH2CA7CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024142556-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMATION METHOD JSR株式会社 2024-07-04 WO disclosed