Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28191378 | 0.92 | DRD4 (0.39) | SIGMAR1DRD4 | |
| SCHEMBL28168592 | 0.92 | DRD4 (0.39) | SIGMAR1DRD4 | |
| Benzene SCHEMBL28236625 | 0.91 | SIGMAR1 (0.40) | SIGMAR1DRD4 | |
| Pyrrole SCHEMBL28240822 | 0.89 | DRD4 (0.38) | SIGMAR1DRD4 | |
| SCHEMBL27450656 | 0.89 | SIGMAR1 (0.39) | SIGMAR1DRD4 | |
| Thiophene SCHEMBL27710669 | 0.86 | DRD4 (0.36) | SIGMAR1DRD4 | |
| Furan SCHEMBL28230613 | 0.85 | DRD4 (0.35) | SIGMAR1DRD4 | |
| Phthalimide SCHEMBL27286842 | 0.85 | PTGIR (0.34) | SIGMAR1DRD4 | |
| SCHEMBL28223991 | 0.84 | CYP1A2 (0.40) | SIGMAR1 | |
| Furan SCHEMBL28211975 | 0.83 | SIGMAR1 (0.36) | SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154105-A | 4-aryl-1-(indanmethyl, dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines, tetrahydropyridines or piperazines | LUNDBECK & CO AS H (DK) | 1997-07-09 | — | — | CN | disclosed |