SCHEMBL27466288

SCHEMBL27466288

CCCCc1ccc(O)c(-n2nc3ccc(C(F)(F)F)cc3n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
LMNA P02545 1/20 0.39
EIF4A1 P60842 1/20 0.39
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
MAPK1 P28482 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PLK1 P53350 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
KAT8 Q9H7Z6 2/20 0.34
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5834556 0.95 KAT8 (0.41) NPC1RAB9ALMNATRPV1PLK1
SCHEMBL2638762 0.89 NPC1 (0.37) NPC1RAB9ALMNAMAPK1HPGD
SCHEMBL2638145 0.87 KDM4E (0.40) NPC1RAB9ALMNAMAPK1HPGD
SCHEMBL13700387 0.84 NPC1 (0.40) NPC1RAB9ALMNANPSR1KDM4E
SCHEMBL3949043 0.83 TMEM97 (0.34) NPC1RAB9ALMNAKDM4EMEN1
SCHEMBL29431672 0.82 NPC1 (0.57) NPC1RAB9ALMNAMAPK1HPGD
SCHEMBL429864 0.82 NPC1 (0.57) NPC1RAB9ALMNAMAPK1HPGD
SCHEMBL2589692 0.82 NPC1 (0.42) NPC1RAB9ALMNAEIF4A1CNR2
SCHEMBL769340 0.82 CNR2 (0.42) NPC1RAB9ALMNACNR1CNR2
SCHEMBL3949046 0.82 MTNR1A (0.38) RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1170824-C Benzotriazole UV absorbent �������⻯ѧƷ�ع����޹�˾ 2004-10-13 CN claimed
CN-1265395-A Benzotriazole UV absorbent CIBA SC HOLDING AG (CH) 2000-09-06 CN claimed
CN-1180008-C Method for content protection using durable UV absorbers �������⻯ѧƷ�ع����޹�˾ 2004-12-15 CN disclosed
CN-1170824-C Benzotriazole UV absorbent �������⻯ѧƷ�ع����޹�˾ 2004-10-13 CN disclosed
CN-1427866-A Method of content protection with durable UV absorbers CIBA SC HOLDING AG (CH) 2003-07-02 CN disclosed
CN-1265395-A Benzotriazole UV absorbent CIBA SC HOLDING AG (CH) 2000-09-06 CN disclosed