Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735305 | 0.93 | CRBN (0.60) | CRBNESR1IKZF2 | |
| SCHEMBL31134571 | 0.93 | CRBN (0.55) | CRBNESR1IKZF2 | |
| SCHEMBL22600233 | 0.93 | CRBN (0.60) | CRBNESR1IKZF2 | |
| SCHEMBL29841272 | 0.93 | CRBN (0.60) | CRBNESR1IKZF2 | |
| SCHEMBL27423839 | 0.93 | CRBN (0.60) | CRBNESR1IKZF2 | |
| Hydrochloric Acid SCHEMBL22581000 | 0.92 | CRBN (0.60) | CRBNESR1IKZF2 | |
| Hydrochloric Acid SCHEMBL22581049 | 0.92 | CRBN (0.60) | CRBNESR1IKZF2 | |
| Hydrochloric Acid SCHEMBL22581144 | 0.92 | CRBN (0.60) | CRBNESR1IKZF2 | |
| SCHEMBL30747132 | 0.92 | CRBN (0.57) | CRBNESR1IKZF2 | |
| SCHEMBL26658501 | 0.92 | CRBN (0.57) | CRBNESR1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565585-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | Bristol-Myers Squibb Company (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024127022-A1 | HETEROCYCLIC COMPOUNDS TARGETING THE NUDT5 PROTEIN | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024030968-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | BRYSTOL-MYERS SQUIBB COMPANY (US) | 2024-02-08 | — | — | WO | disclosed |