Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468379 | 1.00 | CTSA (0.46) | CTSAUSP2CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL27468378 | 1.00 | CTSA (0.46) | CTSAUSP2CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL27467218 | 0.87 | USP2 (0.42) | USP2CYP1A2ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL27468247 | 0.87 | USP2 (0.42) | USP2CYP1A2ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL27468310 | 0.86 | HDAC3 (0.40) | HIF1ACYP3A4P2RY12SMN1; SMN2 | |
| SCHEMBL27467222 | 0.86 | HDAC3 (0.40) | HIF1ACYP3A4P2RY12SMN1; SMN2 | |
| SCHEMBL27468312 | 0.86 | HDAC3 (0.40) | HIF1ACYP3A4P2RY12SMN1; SMN2 | |
| SCHEMBL27468442 | 0.85 | ALDH1A1 (0.49) | USP2CYP1A2ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL27467376 | 0.85 | ALDH1A1 (0.49) | USP2CYP1A2ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL27466907 | 0.82 | HDAC3 (0.46) | CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |