Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481799 | 0.93 | SLC6A4 (0.72) | SLC6A4 | |
| SCHEMBL4670751 | 0.85 | SLC6A4 (0.81) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL12285207 | 0.82 | SLC6A4 (0.67) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL27515398 | 0.82 | SLC6A4 (0.52) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL27465899 | 0.77 | HTR1D (0.60) | SLC6A4KDM4EHTR1AHTR6HTR1D | |
| SCHEMBL7479356 | 0.76 | SLC6A4 (0.76) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL3130981 | 0.76 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| Ammonia Solution, Strong SCHEMBL1122493 | 0.75 | SLC6A4 (0.74) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL6802859 | 0.73 | HTR1D (0.49) | SLC6A4KDM4ELMNAHTR1AALOX15 | |
| SCHEMBL6600009 | 0.73 | HTR1A (0.49) | SLC6A4HTR1AHTR6HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154105-A | 4-aryl-1-(indanmethyl, dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines, tetrahydropyridines or piperazines | LUNDBECK & CO AS H (DK) | 1997-07-09 | — | — | CN | disclosed |