Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCKBR | P32239 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PLD2 | O14939 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467170 | 1.00 | CCR1 (0.50) | CCR1CCKBRPKMPLD2PLD1 | |
| SCHEMBL27468241 | 1.00 | CCR1 (0.50) | CCR1CCKBRPKMPLD2PLD1 | |
| SCHEMBL27467376 | 0.84 | ALDH1A1 (0.49) | CCR1POLBALDH1A1GAAHPGD | |
| SCHEMBL27468442 | 0.84 | ALDH1A1 (0.49) | CCR1POLBALDH1A1GAAHPGD | |
| SCHEMBL27467114 | 0.83 | ACACB (0.47) | CCR1PLD2PLD1 | |
| SCHEMBL27468115 | 0.83 | ACACB (0.47) | CCR1PLD2PLD1 | |
| SCHEMBL27468113 | 0.83 | ACACB (0.47) | CCR1PLD2PLD1 | |
| SCHEMBL27467860 | 0.81 | CCR1 (0.52) | CCR1CCKBR | |
| SCHEMBL27466959 | 0.81 | CCR1 (0.52) | CCR1CCKBR | |
| SCHEMBL27467862 | 0.81 | CCR1 (0.52) | CCR1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |