SCHEMBL27468544

SCHEMBL27468544

C=CC=C(C=C)C(=O)O.[NaH].[NaH]

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
FGFR4 P22455 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492911 0.97
SCHEMBL19578524 0.97
SCHEMBL313661 0.97
SCHEMBL21191374 0.84 LMNA (0.36) LMNA
SCHEMBL19002154 0.81 LMNA (0.38) LMNAALDH1A1TSHRFGFR4ALOX15
SCHEMBL10734660 0.81 LMNA (0.38) LMNAALDH1A1TSHRFGFR4ALOX15
SCHEMBL24088704 0.77 LMNA (0.35) LMNA
SCHEMBL21191444 0.77 LMNA (0.35) LMNA
SCHEMBL22741715 0.77 LMNA (0.35) LMNA
SCHEMBL19017541 0.77 LMNA (0.37) LMNAALDH1A1TSHRFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1165585-C Synthetic polymers comprising additive blends with enhanced effect �������⻯ѧƷ�ع����޹�˾ 2004-09-08 CN disclosed
CN-1336945-A Synthetic polymers comprising additive blends with enhanced effect CIBA SC HOLDING AG (CH) 2002-02-20 CN disclosed