Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638364 | 0.79 | AKR1B1 (0.45) | KDM4EAKR1B1GRM4KMT2AALDH1A1 | |
| SCHEMBL4820867 | 0.79 | PSEN1 (0.57) | KDM4EAKR1B1PSEN1PSEN2APH1B | |
| SCHEMBL865097 | 0.72 | TSHR (0.58) | AKR1B1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14601735 | 0.71 | KDM4E (0.55) | KDM4EAKR1B1PSEN1PSEN2APH1B | |
| SCHEMBL4007057 | 0.70 | MEN1 (0.42) | KDM4EAKR1B1GRM4KMT2AALDH1A1 | |
| SCHEMBL28111261 | 0.69 | MLNR (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26134229 | 0.69 | HTR6 (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3601572 | 0.69 | CA1 (0.46) | KDM4EAKR1B1KMT2AALDH1A1MEN1 | |
| SCHEMBL1272648 | 0.69 | KDM4E (0.37) | KDM4EAKR1B1GRM4KMT2AALDH1A1 | |
| SCHEMBL1500897 | 0.69 | TAAR1 (0.41) | KDM4EAKR1B1GRM4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1132756-A | Antiviral ethers of aspartate protease substrate isosteres | CIBA GEIGY AG (CH) | 1996-10-09 | — | — | CN | disclosed |