Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677713 | 0.90 | IDO1 (0.47) | IDO1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5386714 | 0.82 | IDO1 (0.50) | IDO1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5677981 | 0.81 | IDO1 (0.61) | IDO1FABP4TAS2R14MEN1KMT2A | |
| SCHEMBL7715685 | 0.80 | IDO1 (0.48) | IDO1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27492881 | 0.79 | IDO1 (0.47) | IDO1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6035367 | 0.74 | IDO1 (0.48) | IDO1MAP2K1MAP2K2KMT2ALMNA | |
| SCHEMBL6694982 | 0.73 | MAP2K1 (0.53) | IDO1MAP2K1MAP2K2PTGS1PTGS2 | |
| SCHEMBL15603461 | 0.73 | MAP2K1 (0.70) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL5678007 | 0.73 | IDO1 (0.70) | IDO1MAP2K1MAP2K2MEN1KMT2A | |
| SCHEMBL6035277 | 0.72 | IDO1 (0.44) | IDO1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149204-C | 1-heterocyclic substituted diarylamines | ��ʲ | 2004-05-12 | — | — | CN | disclosed |
| CN-1334807-A | 1-heterocycle substd. diarylamines | WARNER LAMBERT CO (US) | 2002-02-06 | — | — | CN | disclosed |