Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.60 |
| ▸ | ARG2 | P78540 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478223 | 1.00 | ARG1 (0.60) | ARG1ARG2SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL14478224 | 0.90 | ARG1 (0.66) | ARG1ARG2SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL2172319 | 0.89 | SMN1; SMN2 (0.60) | ARG1ARG2SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL9457635 | 0.89 | SMN1; SMN2 (0.60) | ARG1ARG2SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL14743437 | 0.89 | SMN1; SMN2 (0.60) | ARG1ARG2SMN1; SMN2HIF1ASLC6A2 | |
| SCHEMBL5326676 | 0.86 | BLM (0.60) | ARG1ARG2SMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL5326682 | 0.86 | BLM (0.60) | ARG1ARG2SMN1; SMN2HIF1ACYP1A2 | |
| SCHEMBL6724533 | 0.85 | GRM2 (0.47) | ARG1ARG2SMN1; SMN2HIF1ATAAR1 | |
| SCHEMBL11016121 | 0.85 | GRM2 (0.47) | ARG1ARG2SMN1; SMN2HIF1ATAAR1 | |
| SCHEMBL22689266 | 0.85 | ARG1 (0.79) | ARG1ARG2SMN1; SMN2HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151166-A | 3-Amino-2-oxo-1-piperidineacetic acid derivatives as enzyme inhibitors | CORVAS INT INC (US) | 1997-06-04 | — | — | CN | disclosed |