Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Pyruvate SCHEMBL1331224 | 0.92 | — | — | |
| Ethyl Pyruvate SCHEMBL28156490 | 0.92 | GLO1 (0.61) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| Ethyl Pyruvate SCHEMBL25538 | 0.92 | — | — | |
| Ethyl Pyruvate SCHEMBL27732737 | 0.89 | — | — | |
| Ethyl Pyruvate SCHEMBL28214399 | 0.89 | GLO1 (0.58) | GLO1ALDH1A1LMNAHSD17B10CYP2C9 | |
| Ethyl Pyruvate SCHEMBL27622493 | 0.89 | — | — | |
| Ethyl Pyruvate SCHEMBL30913010 | 0.89 | — | — | |
| Ethyl Pyruvate SCHEMBL27450365 | 0.89 | — | — | |
| Ethyl Pyruvate SCHEMBL28039252 | 0.89 | GLO1 (0.58) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| Ethyl Pyruvate SCHEMBL15205901 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162593-A | alpha-iminocarboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1997-10-22 | — | — | CN | disclosed |