Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 5/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032947 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2HIF1ATSHRKIF11ALPI | |
| SCHEMBL27431678 | 0.75 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1AKIF11ALPIPKM | |
| Hydrochloric Acid SCHEMBL9191561 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2HIF1AKIF11ALPIPKM | |
| SCHEMBL8766415 | 0.72 | TSHR (0.42) | TSHRKIF11ALPIPKMPTGS1 | |
| SCHEMBL10866034 | 0.71 | PTPN1 (0.52) | SMN1; SMN2TSHRALDH1A1RAB9ARECQL | |
| SCHEMBL27583884 | 0.71 | PTPN1 (0.52) | SMN1; SMN2TSHRALDH1A1RAB9ARECQL | |
| SCHEMBL10866164 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2HIF1ATSHRKIF11ALPI | |
| SCHEMBL27342313 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2HIF1ATSHRKIF11ALPI | |
| Hydrochloric Acid SCHEMBL27358212 | 0.69 | SMN1; SMN2 (0.45) | SMN1; SMN2HIF1ATSHRKIF11ALPI | |
| SCHEMBL1969122 | 0.67 | KIF11 (0.45) | KIF11ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178953-C | Synthesis and recovery of aspartame involving enzymatic deformylation step | — | 2004-12-08 | — | — | CN | disclosed |
| CN-1335851-A | Synthesis and recovery of aspartame involving enzymatic deformylation step | HOLLAND SWEETENER CO (NL) | 2002-02-13 | — | — | CN | disclosed |